50 ml / 1.7 fl oz | 10 Ingredients
If your skin barrier is struggling, this is one of those products that actually does something about it instead of just sitting pretty on your shelf.
The Epicutis Hydrobiome Serum is formulated to support true skin health by targeting two things I’m always talking about: your microbiome and your barrier. It’s EWG Verified (pending) and built around two clinically studied actives that work with your skin, not against it.
First is TCP, a patented TLR2 modulator from Signum Biosciences. This ingredient helps calm visible irritation while also targeting C. acnes and supporting a healthy balance of your skin’s natural flora. Translation: less inflammation, more harmony where it actually matters.
Then you have TPNa, a next-generation, water-soluble form of Vitamin E. This isn’t your basic antioxidant. It helps protect against oxidative stress and actively strengthens the skin barrier, which is key whether you’re repairing damage or just maintaining healthy skin long-term.
Together, these ingredients help reduce discomfort, rebalance the microbiome, and reinforce the barrier so your skin looks clearer, calmer, and more resilient over time.
The texture is lightweight, absorbs quickly, and layers beautifully into any routine without feeling heavy or occlusive.
What’s doing the work:
• TCP → microbiome support + anti-inflammatory effects
• TPNa → antioxidant protection + barrier strengthening
• Sodium Hyaluronate → immediate hydration boost
• Propanediol → hydration, plumping, and antimicrobial support
This is one of those quiet, foundational products that makes everything else in your routine work better.
Apply two pumps of serum to clean fingertips. Gently spread it evenly over your face until it is fully absorbed. For your neck and décolleté, use an additional pump. For optimal results, use morning and night.
50 ml / 1.7 fl oz | 10 Ingredients
If your skin barrier is struggling, this is one of those products that actually does something about it instead of just sitting pretty on your shelf.
The Epicutis Hydrobiome Serum is formulated to support true skin health by targeting two things I’m always talking about: your microbiome and your barrier. It’s EWG Verified (pending) and built around two clinically studied actives that work with your skin, not against it.
First is TCP, a patented TLR2 modulator from Signum Biosciences. This ingredient helps calm visible irritation while also targeting C. acnes and supporting a healthy balance of your skin’s natural flora. Translation: less inflammation, more harmony where it actually matters.
Then you have TPNa, a next-generation, water-soluble form of Vitamin E. This isn’t your basic antioxidant. It helps protect against oxidative stress and actively strengthens the skin barrier, which is key whether you’re repairing damage or just maintaining healthy skin long-term.
Together, these ingredients help reduce discomfort, rebalance the microbiome, and reinforce the barrier so your skin looks clearer, calmer, and more resilient over time.
The texture is lightweight, absorbs quickly, and layers beautifully into any routine without feeling heavy or occlusive.
What’s doing the work:
• TCP → microbiome support + anti-inflammatory effects
• TPNa → antioxidant protection + barrier strengthening
• Sodium Hyaluronate → immediate hydration boost
• Propanediol → hydration, plumping, and antimicrobial support
This is one of those quiet, foundational products that makes everything else in your routine work better.
Apply two pumps of serum to clean fingertips. Gently spread it evenly over your face until it is fully absorbed. For your neck and décolleté, use an additional pump. For optimal results, use morning and night.
